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Sep 26

SPECT Neuroimaging and Traumatic Brain Injuries: A Look Inside

Written by in Science, Traumatic Brain Injury

SPECT neuroimaging, or single-photon emission tomography may be helpful in the detection and rehabilition for traumatic brain injury. SPECT scans can reveal functional deficits that can be missed by MRI or CT scans.

You can learn more about SPECT neuroimaging and traumatic brain injury here.

The following is from a journal article published on PubMed.gov, Clinical utility of SPECT neuroimaging in the diagnosis and treatment of traumatic brain injury: a systematic review.

We identified 19 longitudinal and 52 cross-sectional studies meeting inclusion criteria. Three longitudinal studies examined diagnostic predictive value. The first showed positive predictive value increases from initial SPECT scan shortly after trauma to one year follow up scans, from 59% to 95%. Subsequent work replicated these results in a larger cohort. Longitudinal and cross sectional studies demonstrated SPECT lesion localization not detected by CT or MRI. The most commonly abnormal regions revealed by SPECT in cross-sectional studies were frontal (94%) and temporal (77%) lobes. SPECT was found to outperform both CT and MRI in both acute and chronic imaging of TBI, particularly mild TBI. It was also found to have a near 100% negative predictive value.

Sources:

amenclinics.com

Raji C.A., Tarzwell R., Pavel D., Schneider H., Uszler M., Thornton J., van Lierop M., Cohen P., Amen D.G., Henderson T.  (2014) Clinical utility of SPECT neuroimaging in the diagnosis and treatment of traumatic brain injury: a systematic review. National Center for Biotechnology Information. http://www.ncbi.nlm.nih.gov/pubmed/24646878 Accessed 2015 September 26.

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